It is necessary for normal endochondral ossification, the process by which the growing skeleton is formed. Mice lacking this gene often exhibit dwarfism and craniofacial abnormalities due to impaired chondrocyte proliferation.
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In many malignancies—including breast, lung, prostate, and gastrointestinal cancers—miR-140 is significantly downregulated. It typically acts as a tumor suppressor by inhibiting cell proliferation, invasion, and metastasis while encouraging cell death (apoptosis). 140 РђРЅРѕРЅСЃ
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Do you need focus on its impact or its oncology/cancer impact? It is necessary for normal endochondral ossification, the
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MicroRNA-140 is highly expressed in cartilage and is a master regulator of chondrocytes (the cells responsible for cartilage formation). Do you need focus on its impact or
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