22948 Rar Apr 2026

: RARA acts as a transcription factor. When it binds to Retinoic Acid (a derivative of Vitamin A), it regulates the expression of genes involved in cell growth, differentiation, and development.

: Understanding this receptor has been a breakthrough in cancer treatment. Patients with APL are often treated with high doses of all-trans retinoic acid (ATRA) , which forces these leukemia cells to mature and die, turning a once-fatal disease into one of the most curable forms of leukemia. 22948 rar

If you tell me more about your specific interest in this gene, I can provide: on its role in embryogenesis. Details on other RAR types (beta or gamma). Information on drug interactions targeting this receptor. : RARA acts as a transcription factor

: It is most famous for its role in Acute Promyelocytic Leukemia (APL) . In most cases of APL, a piece of chromosome 15 (containing the PML gene) and a piece of chromosome 17 (containing the RARA gene) swap places. This creates a fusion protein called PML-RARA , which prevents immature white blood cells from maturing properly. Patients with APL are often treated with high

The gene provides instructions for making a protein called the retinoic acid receptor alpha, which is a nuclear receptor critical for various biological processes.