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"465K.txt" is a data file from the 2016 Genome Biology paper "deconstructSigs: delineating mutational processes in single tumors" by Rosenthal et al., which introduces an R package for identifying mutational signatures in individual cancer samples. The file contains TCGA tumor sample data, detailing specific signature weights for validating the methodology against the WTSI framework. Read the full research paper at Europe PMC .

465k.txt Apr 2026

"465K.txt" is a data file from the 2016 Genome Biology paper "deconstructSigs: delineating mutational processes in single tumors" by Rosenthal et al., which introduces an R package for identifying mutational signatures in individual cancer samples. The file contains TCGA tumor sample data, detailing specific signature weights for validating the methodology against the WTSI framework. Read the full research paper at Europe PMC .

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