Amyloid Protein Plaque 📥

: Enzymes called secretases (specifically β-secretase and γ-secretase) cut APP into smaller fragments.

: These sticky fragments clump together, first forming small groups called oligomers, and eventually maturing into the large, dense deposits known as senile plaques . 2. Impact on Brain Function amyloid protein plaque

New FDA-approved blood tests for diagnosing Alzheimer's disease first forming small groups called oligomers

Amyloid protein plaques are hard, insoluble accumulations of proteins that build up in the spaces between nerve cells (neurons) in the brain. Considered a primary hallmark of Alzheimer's Disease (AD) , these plaques disrupt critical cell-to-cell communication and trigger a cascade of neurodegeneration. 1. How Plaques Form and eventually maturing into the large