Many agents, such as polyenes (e.g., Amphotericin B), bind to ergosterol , a sterol unique to fungal membranes, creating pores that cause the cell to leak and die.
The choice of an antimycotic agent depends heavily on the infection's location and severity. Antifungal Agents - StatPearls - NCBI Bookshelf - NIH antimycotic agent
Echinocandins (e.g., caspofungin) target the fungal cell wall by inhibiting the synthesis of β-(1,3)-D-glucan, a critical structural component. Clinical Applications and Administration Many agents, such as polyenes (e