: Studies in December 2006 highlighted that frequent high-dose use is associated with brain damage , specifically reduced levels of serotonin transporters.
: Discussions and production began around this time for film adaptations of related literature, such as Irvine Welsh's Ecstasy . Extasy 09 (2006)
: Research published in late 2006 identified patterns of ecstasy-associated hyponatremia (dangerously low sodium levels), often occurring in female users. : Studies in December 2006 highlighted that frequent
In 2006, significant archival research was published to clarify the true history of MDMA's discovery. Extasy 09 (2006)