An overview of the pharmacokinetics and promising biological activities for cancer therapy in both humans and animals. Oral Fenbendazole for Cancer Therapy .
The drug interferes with tubulin polymerization, a process essential for cancer cell division.
It may block glucose uptake in cancer cells by downregulating GLUT transporters , effectively "starving" the tumor.
However, the primary research paper often cited by that community regarding the drug's potential anti-cancer mechanisms is:
Source: Nature Scientific Reports / PubMed Central Date: August 9, 2018 Key Findings:
It promotes the activation of the p53 tumor suppressor protein, leading to programmed cell death (apoptosis). Other Notable Papers
Research indicating that the drug may target cancer stem cells, which are often resistant to standard treatments. Fenbendazole Exhibits Antitumor Activity Against Cervical Cancer .
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