Cristina begins a relationship with cardiothoracic surgeon Dr. Preston Burke.
(T.R. Knight): Insecure but kind, he harbors a secret crush on Meredith.
(Justin Chambers): Initially seen as a mean-spirited bully.
The blossoming but complicated romance between Meredith and "McDreamy" (Derek).
(Katherine Heigl): A former model who struggles to be taken seriously.
(Sandra Oh): Highly competitive and ambitious.
Throughout the first few months of their program, these doctors face life-or-death medical cases while discovering that neither medicine nor their relationships can be defined in simple black and white. AI responses may include mistakes. Learn more