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: Palovarotene (brand name Sohonos ) is a selective RAR-γ (retinoic acid receptor gamma) agonist. It is the first approved treatment for FOP, a rare genetic disorder where bone forms in muscles and soft tissues.
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Palovarotene (Sohonos), a synthetic retinoid for reducing new ... - PMC : Palovarotene (brand name Sohonos ) is a
: A significant concern highlighted in recent reviews is premature growth plate closure , which has been observed in approximately 35% of pediatric patients under 14 years of age. it is approved in the U.S.
: As of early 2026, it is approved in the U.S., Canada, and Australia for specific age groups (males ≥ 10, females ≥ 8). Potential Non-Medical Interpretations