Mercedes S-class W221 1.45 Apr 2026

The , produced from 2006 to 2013 , is widely considered one of the finest luxury flagships of its era, marking a significant return to form for Mercedes after the reliability criticisms of the previous W220 model. While it offers exceptional comfort and pioneering technology, it requires a "luxury maintenance" budget to remain reliable on the used market. Key Highlights

: Uses infrared technology to see pedestrians at night. MERCEDES S-CLASS W221 1.45

Reliability varies significantly by the engine and production year. The (Phase 2) is generally recommended as it resolved several early mechanical issues. The , produced from 2006 to 2013 ,

: Predicts collisions and can automatically apply maximum braking pressure. : The cabin replaced many plastic surfaces with

: The cabin replaced many plastic surfaces with higher-end leather, wood, and metal. High-end options include massaging seats with four modes and active ventilation. Engine Options & Reliability

: An advanced adaptive cruise control that can bring the car to a full stop in traffic.

: This generation introduced several high-tech features still impressive today: