According to the One Piece Wiki , the anime expands on several scenes not detailed in the manga:
After suffering a near-fatal nosebleed in the previous episode, Sanji receives a life-saving blood transfusion from two generous human donors, Splash and Splatter. Finding a donor is a significant struggle due to the deep-seated history of slavery and the resulting illegal nature of blood sharing between humans and Fish-Men. One Piece Episode 529
One Piece Episode 529, titled , is a pivotal entry in the Fish-Man Island Arc that shifts the tone from lighthearted reunion to looming catastrophe. Key Episode Details Original Air Date: December 25, 2011. Manga Counterpart: Corresponds to Chapter 610. Current Arc: Fish-Man Island (Season 15, Episode 13). Major Plot Points According to the One Piece Wiki , the
Luffy, Usopp, and Brook travel with Pappag to his luxurious home in Gyoverly Hills. During the tour, they learn more about the island's protection, which shifted from Whitebeard to Big Mom after the Paramount War. Key Episode Details Original Air Date: December 25, 2011
Extended scenes of frantically calling out for blood donors across the island.
A flashback showing how arrived at Fish-Man Island and met Pappag.