If you are stuck on a puzzle piece in this version, it likely involves the or Police Station areas which were focal points of early updates.
If you are looking for a related to this specific file, it typically refers to one of two things: The_Genesis_Order-PC-v.04122.UPDATE.ONLY.zip
This specific version was part of the game's early access development (roughly around 4% completion). If you are stuck on a puzzle piece
If this is an "Update Only" file, you must have the base game already installed. You typically copy the contents of this zip into your existing game folder and replace the old files to apply the "piece" of the update. The_Genesis_Order-PC-v.04122.UPDATE.ONLY.zip