The community faces specific, persistent stressors related to prejudice and discrimination, according to data from the National Institutes of Health (NIH) .

A high-quality, in-depth report looking at the transgender community and LGBTQ culture is the , conducted by Advocates for Trans Equality (A4TE, formerly the National Center for Transgender Equality).

According to Gallup Data updated in 2025, over 9% of U.S. adults now identify as LGBTQ+, a significant increase from previous decades.